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A case of cerebral infarction due to pleomorphic carcinoma of the lung

Background: With the increase in endovascular treatment, reports of embolism other than thrombus are scattered, but intracranial tumorigenic embolism is rare and difficult to diagnose. Here, we describe a case of a tumorigenic embolism in a patient with lung cancer whose invasion into the vascular s...

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Bibliographic Details
Published in:Surgical neurology international 2020-08, Vol.11, p.217, Article 217
Main Authors: Yoshikawa, Shinichiro, Kamide, Tomoya, Kasakura, Shigen, Arai, Noriko, Osada, Takashi, Mouri, Atsuto, Hamada, Mei, Kawasaki, Tomonori, Takao, Masaki, Kohyama, Shinya
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Language:English
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Summary:Background: With the increase in endovascular treatment, reports of embolism other than thrombus are scattered, but intracranial tumorigenic embolism is rare and difficult to diagnose. Here, we describe a case of a tumorigenic embolism in a patient with lung cancer whose invasion into the vascular system was not detected on preoperative whole-body imaging. Case Description: A 66-year-old man who was hospitalized to undergo radiotherapy for pulmonary carcinoma suddenly developed left hemiplegia. He exhibited atrial fibrillation, and emergent radiographic examination revealed a right middle cerebral artery occlusion. Urgent mechanical embolectomy was performed, with successful revascularization. The excised embolus had a unique morphology and was pathologically diagnosed as a cerebral embolism caused by pleomorphic pulmonary carcinoma. Conclusion: Tumor-derived cerebral embolism is extremely rare, but it is necessary to consider it as a potential source of embolism during differential diagnosis in patients with malignant tumors.
ISSN:2152-7806
2229-5097
2152-7806
DOI:10.25259/SNI_37_2020