Adverse Drug Reactions in Patients with CKD

Little is known about the burden of adverse drug reactions in CKD. We estimated the incidence of overall and serious adverse drug reactions and assessed the probability of causation, preventability, and factors associated with adverse drug reactions in patients seen by nephrologists. The Chronic Kid...

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Bibliographic Details
Published in:Clinical journal of the American Society of Nephrology 2020-08, Vol.15 (8), p.1090-1102
Main Authors: Laville, Solène M, Gras-Champel, Valérie, Moragny, Julien, Metzger, Marie, Jacquelinet, Christian, Combe, Christian, Fouque, Denis, Laville, Maurice, Frimat, Luc, Robinson, Bruce M, Stengel, Bénédicte, Massy, Ziad A, Liabeuf, Sophie
Format: Article
Language:English
Subjects:
Aged
Angiotensin Receptor Antagonists - adverse effects
Angiotensin-Converting Enzyme Inhibitors - adverse effects
Diuretics - adverse effects
Drug-Related Side Effects and Adverse Reactions - diagnosis
Drug-Related Side Effects and Adverse Reactions - epidemiology
Drug-Related Side Effects and Adverse Reactions - mortality
Drug-Related Side Effects and Adverse Reactions - prevention & control
Female
Fibrinolytic Agents - adverse effects
France - epidemiology
Human health and pathology
Humans
Incidence
Life Sciences
Male
Middle Aged
Original
Pharmaceutical sciences
Pharmacology
Polypharmacy
Prospective Studies
Renal Insufficiency, Chronic - diagnosis
Renal Insufficiency, Chronic - drug therapy
Renal Insufficiency, Chronic - mortality
Risk Assessment
Risk Factors
Severity of Illness Index
Time Factors
Urology and Nephrology
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Description
Summary:Little is known about the burden of adverse drug reactions in CKD. We estimated the incidence of overall and serious adverse drug reactions and assessed the probability of causation, preventability, and factors associated with adverse drug reactions in patients seen by nephrologists. The Chronic Kidney Disease-Renal Epidemiology and Information Network cohort included 3033 outpatients (65% men) with CKD and eGFR
ISSN:1555-9041
1555-905X
DOI:10.2215/CJN.01030120