Aortic Knob Width: A Possible Marker of Vascular Remodeling in Obstructive Sleep Apnea

Obstructive sleep apnea (OSA) is characterized by recurrent episodes of upper airway collapse during sleep, resulting in apneas or hypopneas. Several cohort studies have recently shown that severe OSA is independently associated with an increased risk of myocardial infarction, stroke, and death from...

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Bibliographic Details
Published in:Journal of Atherosclerosis and Thrombosis 2020/06/01, Vol.27(6), pp.499-500
Main Authors: Shiina, Kazuki, Tomiyama, Hirofumi, Takata, Yoshifumi, Chikamori, Taishiro
Format: Article
Language:eng ; jpn
Subjects:
Aorta - diagnostic imaging
Aorta - pathology
Correlation of Data
Early Diagnosis
Humans
Organ Size
Polysomnography - methods
Radiography, Thoracic - methods
Severity of Illness Index
Sleep Apnea, Obstructive - diagnosis
Sleep Apnea, Obstructive - physiopathology
Vascular Remodeling
Vascular Stiffness
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Summary:Obstructive sleep apnea (OSA) is characterized by recurrent episodes of upper airway collapse during sleep, resulting in apneas or hypopneas. Several cohort studies have recently shown that severe OSA is independently associated with an increased risk of myocardial infarction, stroke, and death from cardiovascular disease. The possible mechanisms underlying OSA contribution to atherosclerosis comprise complex and interrelated cascades. Therefore, it is difficult to elucidate the causal relationship between OSA and atherosclerosis. Among these mechanisms, intermittent hypoxia is believed to be the main component linking OSA to atherosclerosis.
ISSN:1340-3478
1880-3873
DOI:10.5551/jat.ED123