The First Known Case of Liver Abscess Caused by Aggregatibacter aphrophilus in Japan

A 48-year-old man presented with a sustained fever. Abdominal computed tomography revealed multilocular liver abscesses. He underwent percutaneous needle aspiration, yielding straw-colored pus. Gram staining revealed Gram-negative coccobacilli. The organism grew only on chocolate II agar in a 7% car...

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Bibliographic Details
Published in:Internal Medicine 2020/06/01, Vol.59(11), pp.1451-1455
Main Authors: Okumura, Taiki, Soya, Keisuke, Hihara, Yu, Muraoka, Shinji, Nishimura, Yoshihiro, Inoue, Katsuaki, Maruyama, Atsushi, Matsumoto, Go
Format: Article
Language:English
Subjects:
Abscesses
Aggregatibacter aphrophilus
Antibiotics
Carbon dioxide
Case Report
Computed tomography
Fever
Internal medicine
Liver
liver abscess
Mass spectrometry
Mass spectroscopy
rRNA 16S
Scientific imaging
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Summary:A 48-year-old man presented with a sustained fever. Abdominal computed tomography revealed multilocular liver abscesses. He underwent percutaneous needle aspiration, yielding straw-colored pus. Gram staining revealed Gram-negative coccobacilli. The organism grew only on chocolate II agar in a 7% carbon dioxide atmosphere. Identification of Aggregatibacter aphrophilus was confirmed using mass spectrometry and 16S rRNA gene sequencing. He was successfully treated with antibiotics. Liver abscess caused by A. aphrophilus is extremely rare. We herein report the first such case in Japan. Even fastidious organisms, such as A. aphrophilus, should be correctly identified using mass spectrometry or 16S rRNA gene sequencing for adequate treatment.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.4220-19