Serum IL-6: A biomarker in childhood asthma?

Serum IL-6 was associated with asthma exacerbation risk but not with symptoms or lung function in urban children; further studies to evaluate the role of IL-6 in the life course of asthma are needed.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2020-06, Vol.145 (6), p.1701-1704.e3
Main Authors: Jackson, Daniel J., Bacharier, Leonard B., Calatroni, Agustin, Gill, Michelle A., Hu, Jack, Liu, Andrew H., Wheatley, Lisa M., Gern, James E., Gruchalla, Rebecca S., Khurana Hershey, Gurjit K., Kattan, Meyer, Kercsmar, Carolyn M., Kim, Haejin, O’Connor, George T., Patel, Shilpa, Pongracic, Jacqueline A., Wood, Robert A., Busse, William W.
Format: Article
Language:English
Subjects:
Adolescent
Asthma - blood
Biomarkers - blood
Child
Cross-Sectional Studies
Female
Humans
Inflammation - blood
Interleukin-6 - blood
Male
Signal Transduction - physiology
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Description
Summary:Serum IL-6 was associated with asthma exacerbation risk but not with symptoms or lung function in urban children; further studies to evaluate the role of IL-6 in the life course of asthma are needed.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2020.01.021