Hand sanitisers amid CoViD-19: A critical review of alcohol-based products on the market and formulation approaches to respond to increasing demand

The world is facing a medical crisis amid the CoViD-19 pandemic and the role of adequate hygiene and hand sanitisers is inevitable in controlling the spread of infection in public places and healthcare institutions. There has been a great surge in demand for hand sanitisation products leading to sho...

Full description

Saved in:
Bibliographic Details
Published in:International journal of pharmaceutics 2020-06, Vol.584, p.119431-119431
Main Authors: Berardi, Alberto, Perinelli, Diego R, Merchant, Hamid A, Bisharat, Lorina, Basheti, Iman A, Bonacucina, Giulia, Cespi, Marco, Palmieri, Giovanni F
Format: Article
Language:English
Subjects:
Alcohols - chemistry
Coronavirus Infections - prevention & control
COVID-19
Disinfectants - chemistry
Disinfectants - therapeutic use
Drug Compounding
Hand Disinfection - methods
Hand Hygiene - methods
Humans
Pandemics - prevention & control
Pneumonia, Viral - prevention & control
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The world is facing a medical crisis amid the CoViD-19 pandemic and the role of adequate hygiene and hand sanitisers is inevitable in controlling the spread of infection in public places and healthcare institutions. There has been a great surge in demand for hand sanitisation products leading to shortages in their supply. A consequent increase of substandard products in the market has raised safety concerns. This article, therefore, presents a critical review of hand sanitation approaches and products available on the market in light of the scientific evidence available to date. This review also provides a range of hand sanitisation product formulations, and manufacturing instructions to allow for extemporaneous preparations at the community and hospital pharmacies during this urgent crisis. In addition, this emergent situation is expected to continue, hence hand sanitisers will be in demand for an extended time, and the availability and purchase of substandard products on the market create an ongoing safety concern. Therefore, this article shall also provide various commercial organisations, interested in stepping forward the production and marketing of hand sanitisers, with a guide on the development of products of standardised ingredients and formulations.
ISSN:0378-5173
1873-3476
DOI:10.1016/j.ijpharm.2020.119431