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Automatically Enhanced OCT Scans of the Retina: A proof of concept study

In this work we evaluated a postprocessing, customized automatic retinal OCT B-scan enhancement software for noise reduction, contrast enhancement and improved depth quality applicable to Heidelberg Engineering Spectralis OCT devices. A trained deep neural network was used to process images from an...

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Bibliographic Details
Published in:Scientific reports 2020-05, Vol.10 (1), p.7819-7819, Article 7819
Main Authors: Apostolopoulos, Stefanos, Salas, Jazmín, Ordóñez, José L P, Tan, Shern Shiou, Ciller, Carlos, Ebneter, Andreas, Zinkernagel, Martin, Sznitman, Raphael, Wolf, Sebastian, De Zanet, Sandro, Munk, Marion R
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Language:English
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Summary:In this work we evaluated a postprocessing, customized automatic retinal OCT B-scan enhancement software for noise reduction, contrast enhancement and improved depth quality applicable to Heidelberg Engineering Spectralis OCT devices. A trained deep neural network was used to process images from an OCT dataset with ground truth biomarker gradings. Performance was assessed by the evaluation of two expert graders who evaluated image quality for B-scan with a clear preference for enhanced over original images. Objective measures such as SNR and noise estimation showed a significant improvement in quality. Presence grading of seven biomarkers IRF, SRF, ERM, Drusen, RPD, GA and iRORA resulted in similar intergrader agreement. Intergrader agreement was also compared with improvement in IRF and RPD, and disagreement in high variance biomarkers such as GA and iRORA.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-64724-8