Surveillance of 16 respiratory viruses in patients with influenza-like illness in Nanjing, China

Much less is known about the etiology of influenza‐like illness in China. A continuous surveillance of 16 respiratory viruses was conducted from November 2010 to October 2011 of outpatients with influenza‐like illness in Nanjing, China. The two largest general hospitals and a provincial virus labora...

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Bibliographic Details
Published in:Journal of medical virology 2012-12, Vol.84 (12), p.1980-1984
Main Authors: Huo, Xiang, Qin, Yuanfang, Qi, Xian, Zu, Rongqiang, Tang, Fenyang, Li, Liang, Hu, Zhibin, Zhu, Fengcai
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Child
Child, Preschool
China - epidemiology
Coinfection - diagnosis
Coinfection - virology
DNA, Viral - genetics
Enterovirus - isolation & purification
Epidemiology
Fundamental and applied biological sciences. Psychology
Human viral diseases
Humans
Infant
Infectious diseases
Influenza, Human - diagnosis
Influenza, Human - epidemiology
Influenza, Human - virology
influenza-like illness
Medical sciences
Microbiology
Middle Aged
Miscellaneous
Orthomyxoviridae - isolation & purification
outpatients
Picornaviridae Infections - diagnosis
Picornaviridae Infections - epidemiology
Picornaviridae Infections - virology
Polymerase Chain Reaction
Population Surveillance - methods
Respiratory Syncytial Virus Infections - diagnosis
Respiratory Syncytial Virus Infections - epidemiology
Respiratory Syncytial Virus Infections - virology
Respiratory Syncytial Viruses - isolation & purification
Respiratory Tract Diseases - diagnosis
Respiratory Tract Diseases - epidemiology
Respiratory Tract Diseases - virology
respiratory viruses
Rhinovirus - isolation & purification
RNA, Viral - genetics
Seasons
surveillance
Viral diseases
Virology
Young Adult
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Summary:Much less is known about the etiology of influenza‐like illness in China. A continuous surveillance of 16 respiratory viruses was conducted from November 2010 to October 2011 of outpatients with influenza‐like illness in Nanjing, China. The two largest general hospitals and a provincial virus laboratory in Nanjing participated in this study. Throat swabs were collected from outpatients during medical visits for influenza‐like illness and were tested for 16 respiratory viruses using PCR. Three hundred seventeen viruses were detected in samples from 246 (50.6%) patients with influenza‐like illness. The viruses found mostly commonly were influenza, rhinovirus, hCoV HKU1, and adenovirus. The identification rates of respiratory viruses differed significantly among different sampling seasons (P = 0.0002). The rates of influenza A and hCoV HKU1 were much higher during the influenza‐like illness winter peak than during the influenza‐like illness summer peak and other months. Co‐infections were detected in 57 (11.7%) patients and were found most commonly in adults older than 60 years. RSV was detected in 5.9% and 2.6% of patients who were 0–5 and 6–15 years old, respectively, but was not detected in other age groups. This study confirmed that multiple respiratory viruses may circulate concurrently in the population and account for a large proportion of influenza‐like illness. In addition to influenza virus, hCoV HKU1 may be associated with the influenza‐like illness winter peak in Nanjing, China. J. Med. Virol. 84:1980–1984, 2012. © 2012 Wiley Periodicals, Inc.
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.23401