Dendritic DNA Building Blocks for Amplified Detection Assays and Biomaterials

DNA branches out: Recent advances in the assembly of dendritic DNA structures enable applications in biosensing of pathogens and the generation of novel pads of DNA hydrogel biomaterials (see scheme, left). These pads are immersed in a cell extract containing RNA polymerase (red), ribosomes (yellow)...

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Bibliographic Details
Published in:Angewandte Chemie (International ed.) 2009-01, Vol.48 (33), p.5996-6000
Main Authors: Feldkamp, Udo, Saccà, Barbara, Niemeyer, Christof M
Format: Article
Language:English
Subjects:
Anisotropy
Biosensing Techniques
dendrimers
Dendrimers - chemistry
DNA - chemistry
DNA structures
gels
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Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry
nanotechnology
Nucleic Acid Conformation
Protein Biosynthesis
proteins
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Summary:DNA branches out: Recent advances in the assembly of dendritic DNA structures enable applications in biosensing of pathogens and the generation of novel pads of DNA hydrogel biomaterials (see scheme, left). These pads are immersed in a cell extract containing RNA polymerase (red), ribosomes (yellow), and other components for in vitro protein biosynthesis, where they can be used as templates for cell‐free protein production.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200902285