Dosimetric evaluation of the heart and left anterior descending artery dose in radiotherapy for Japanese patients with breast cancer

Abstract Intensity-modulated radiotherapy (IMRT) has been used for breast cancer as well as in field-in-field techniques. Few dosimetric comparison studies have been conducted using IMRT and volumetric modulated arc therapy (VMAT) for Japanese patients. We aimed to study such patients. Thirty-two pa...

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Bibliographic Details
Published in:Journal of radiation research 2020-01, Vol.61 (1), p.134-139
Main Authors: Tanaka, Osamu, Ono, Kousei, Taniguchi, Takuya, Makita, Chiyoko, Matsuo, Masayuki
Format: Article
Language:English
Subjects:
Breast cancer
Cancer
Cancer patients
Care and treatment
Diagnosis
Lumpectomy
Oncology, Experimental
Radiotherapy
Regular Paper
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Summary:Abstract Intensity-modulated radiotherapy (IMRT) has been used for breast cancer as well as in field-in-field techniques. Few dosimetric comparison studies have been conducted using IMRT and volumetric modulated arc therapy (VMAT) for Japanese patients. We aimed to study such patients. Thirty-two patients with left-sided breast cancer were enrolled. We conducted the following five treatment plans: two field-static IMRT (2F-S-IMRT), four field-static IMRT (4F-S-IMRT), 40° dual partial arc VMAT (40d-VMAT), 80° dual partial arc VMAT (80d-VMAT) and 210° partial VMAT (210p-VMAT). We evaluated the following: level of coverage of planning target volume (PTV) of 95% for irradiation at a dose of 50 Gy (D95) and the percentage of the heart and left anterior descending artery (LAD) volume that received 10 Gy or more (V10). As a result, the coverage of 40d-VMAT for the prescribed PTV dose of D95 was significantly lower than that of the other treatment plans (P 
ISSN:0449-3060
1349-9157
DOI:10.1093/jrr/rrz087