Recovery and prognostic value of myocardial strain in ST-segment elevation myocardial infarction patients with a concurrent chronic total occlusion

Objectives Global left ventricular (LV) function is routinely used to assess cardiac function; however, myocardial strain is able to identify more subtle dysfunction. We aimed to determine the recovery and prognostic value of featuring tracking (FT) cardiovascular magnetic resonance (CMR) strain in...

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Bibliographic Details
Published in:European radiology 2020-01, Vol.30 (1), p.600-608
Main Authors: Elias, Joëlle, van Dongen, Ivo M., Hoebers, Loes P., Ouweneel, Dagmar M., Claessen, Bimmer E. P. M., Råmunddal, Truls, Laanmets, Peep, Eriksen, Erlend, Piek, Jan J., van der Schaaf, René J., Ioanes, Dan, Nijveldt, Robin, Tijssen, Jan G., Henriques, José P. S., Hirsch, Alexander
Format: Article
Language:English
Subjects:
Cardiac
Coronary Occlusion - complications
Coronary Occlusion - diagnostic imaging
Coronary Occlusion - physiopathology
Diagnostic Radiology
Electrocardiography
Female
Heart
Heart - diagnostic imaging
Heart - physiology
Heart attacks
Humans
Imaging
Internal Medicine
Interventional Radiology
Magnetic resonance
Magnetic Resonance Imaging - methods
Male
Mathematical analysis
Medicine
Medicine & Public Health
Middle Aged
Myocardial infarction
Neuroradiology
Occlusion
Parameters
Patients
Prognosis
Radiology
Recovery
Recovery (Medical)
Recovery of function
Reproducibility of Results
ST Elevation Myocardial Infarction - complications
ST Elevation Myocardial Infarction - diagnostic imaging
ST Elevation Myocardial Infarction - physiopathology
Stroke Volume
Territory
Thickening
Ultrasound
Ventricle
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Summary:Objectives Global left ventricular (LV) function is routinely used to assess cardiac function; however, myocardial strain is able to identify more subtle dysfunction. We aimed to determine the recovery and prognostic value of featuring tracking (FT) cardiovascular magnetic resonance (CMR) strain in ST-segment elevation myocardial infarction (STEMI) patients with a concurrent chronic total occlusion (CTO). Methods In the randomized EXPLORE trial, there was no significant difference in global LV function after percutaneous coronary intervention (PCI) of the CTO, compared with no-CTO PCI, post-STEMI. In the current study, we included 200 of the 302 EXPLORE patients with a baseline CMR, of which 180 also had 4-month follow-up (serial) CMR. Global longitudinal strain (GLS) was calculated from 3 long-axis views. Global circumferential strain (GCS) and segmental strain were calculated from 3 short-axis views (basal, mid, and apical). Results Global strain significantly improved at 4 months (GLS ∆ − 1.8 ± 4.3%, p  
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-019-06338-x