Integrative proteomics and pharmacogenomics analysis of methylphenidate treatment response

Transcriptomics and candidate gene/protein expression studies have indicated several biological processes modulated by methylphenidate (MPH), widely used in attention-deficit/hyperactivity disorder (ADHD) treatment. However, the lack of a differential proteomic profiling of MPH treatment limits the...

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Bibliographic Details

Published in:	Translational psychiatry 2019-11, Vol.9 (1), p.308-13, Article 308
Main Authors:	da Silva, Bruna S, Leffa, Douglas T, Beys-da-Silva, Walter O, Torres, Iraci L S, Rovaris, Diego L, Victor, Marcelo M, Rohde, Luis A, Mota, Nina R, Oliveira, Carla de, Berger, Markus, Yates, 3rd, John R, Sabnis, Renuka, Peña, Ramón Díaz, Campos, Alexandre Rosa, Grevet, Eugenio H, Santi, Lucelia, Bau, Claiton H D, Contini, Verônica
Format:	Article
Language:	English
Subjects:	Adult Animals Attention Deficit Disorder with Hyperactivity - drug therapy Attention Deficit Disorder with Hyperactivity - genetics Attention Deficit Hyperactivity Disorder Central Nervous System Stimulants - therapeutic use Female Humans Male Methylphenidate - therapeutic use Pharmacogenetics Proteomics Random Allocation Rats Rats, Inbred WKY
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