Thyroid nodules with Hürthle cells: the malignancy risk in relation to the FNA outcome category

Purpose The aim was to find whether the presence of Hürthle cells (HC) in a smear influences the categorization of FNA results or the risk of malignancy (RoM) of particular categories of cytological diagnosis. Methods 25,220 FNA performed in a single center in years 2005–2017 were analyzed. Almost a...

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Bibliographic Details
Published in:Journal of endocrinological investigation 2019-11, Vol.42 (11), p.1319-1327
Main Authors: Słowińska-Klencka, D., Wysocka-Konieczna, K., Woźniak-Oseła, E., Sporny, S., Popowicz, B., Sopiński, J., Kaczka, K., Kuzdak, K., Pomorski, L., Klencki, M.
Format: Article
Language:English
Subjects:
Adenocarcinoma, Follicular - diagnosis
Adenocarcinoma, Follicular - surgery
Biopsy, Fine-Needle - methods
Cytodiagnosis - methods
Endocrinology
Female
Follow-Up Studies
Humans
Internal Medicine
Iodine
Male
Malignancy
Medicine
Medicine & Public Health
Metabolic Diseases
Middle Aged
Nodules
Original
Original Article
Oxyphil Cells - pathology
Prognosis
Thyroid
Thyroid Gland - pathology
Thyroid Gland - surgery
Thyroid Neoplasms - classification
Thyroid Neoplasms - diagnosis
Thyroid Neoplasms - surgery
Thyroid Nodule - diagnosis
Thyroid Nodule - surgery
Thyroidectomy
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Summary:Purpose The aim was to find whether the presence of Hürthle cells (HC) in a smear influences the categorization of FNA results or the risk of malignancy (RoM) of particular categories of cytological diagnosis. Methods 25,220 FNA performed in a single center in years 2005–2017 were analyzed. Almost all the examined patients were exposed to moderate iodine deficiency for most of their lives. The distribution of FNA outcome categories was compared between two groups: with or without HC (HC and non-HC). The RoM was evaluated on the basis of postoperative histopathological examination (3082 patients). Results HC were found in 7.5% of diagnostic FNA. HC nodules were classified into categories II (78.2% vs. 91.9%, p  
ISSN:1720-8386
0391-4097
1720-8386
DOI:10.1007/s40618-019-01055-0