Acute myeloid leukaemia presenting as acute liver failure—a case report and literature review

A 75-year-old woman presented with rapidly progressive fatigue, abdominal pain and jaundice. Physical examination revealed tender abdomen and splenomegaly. Magnetic resonance cholangiogram showed marked hepatomegaly, splenomegaly and scattered nodules or masses in the liver and spleen. The patient e...

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Bibliographic Details
Published in:Ecancermedicalscience 2019-09, Vol.13
Main Authors: Sun, Kai, Reynolds, Ryan J, Sheu, Tiffany G, Tomsula, Jessica A, Colton, Lara, Rice, Lawrence
Format: Article
Language:English
Subjects:
Abdomen
Blood
Bone marrow
Case Report
Case reports
Chemotherapy
Family medical history
Flow cytometry
Hematology
Hemoglobin
Hospitals
Leukemia
Liver
Lymphoma
Mortality
Neutrophils
Patients
Phosphatase
Spleen
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Description
Summary:A 75-year-old woman presented with rapidly progressive fatigue, abdominal pain and jaundice. Physical examination revealed tender abdomen and splenomegaly. Magnetic resonance cholangiogram showed marked hepatomegaly, splenomegaly and scattered nodules or masses in the liver and spleen. The patient expired from multiorgan failure. Autopsy revealed infiltration of the liver, spleen and bone marrow by acute myeloid leukaemia.
ISSN:1754-6605
1754-6605
DOI:10.3332/ecancer.2019.960