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Utility of transthoracic impedance and novel algorithm for sleep apnea screening in pacemaker patient

Background Pacing patients was revealed with a high prevalence of sleep disorder, but mostly undiagnosed. The pacemaker with transthoracic impedance sensor and novel algorithm could identify sleep apnea (SA) event. This study aimed to evaluate accuracy of pacemaker in sleep apnea diagnosis. Methods...

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Bibliographic Details
Published in:Sleep & breathing 2019-09, Vol.23 (3), p.741-746
Main Authors: Chen, RuoHan, Chen, KePing, Dai, Yan, Zhang, Shu
Format: Article
Language:English
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Summary:Background Pacing patients was revealed with a high prevalence of sleep disorder, but mostly undiagnosed. The pacemaker with transthoracic impedance sensor and novel algorithm could identify sleep apnea (SA) event. This study aimed to evaluate accuracy of pacemaker in sleep apnea diagnosis. Methods This is a prospective study which enrolled patients implanted with pacemakers integrated with transthoracic impedance sensor and SA-identified algorithm (AP Scan). All patients underwent a polysomnography (PSG). The apnea and hypopnea index (AHI) of the PSG (PSG-AHI) and the respiratory disturbance index (RDI) of the pacemaker (PM-RDI) were recorded on the same night. The correlation between two methods was evaluated by the kappa coefficient, receiver operating characteristic (ROC) curves, and Bland and Altman statistics. Results Sixty-four patients were enrolled, who had never been diagnosed with SAS or underwent PSG exam. After PSG examination, 76.4% patients were diagnosed as combining with SA (20% severe, 18.2% moderate, and 38.2% mild). RDI calculated by PM has a strong positive correlation with PSG-AHI ( r  = 0.76, p  
ISSN:1520-9512
1522-1709
DOI:10.1007/s11325-018-1755-y