Historical Evolution of the Polymorphous Adenocarcinoma

The 2017 World Health Organization Classification of Head and Neck Tumors introduced for the first time the diagnostic terminology “cribriform variant of polymorphous adenocarcinoma”. This nomenclature attempts to reconciliate the ongoing taxonomical controversy related to cribriform adenocarcinoma...

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Bibliographic Details
Published in:	Head & neck pathology (Totowa, N.J.) N.J.), 2019-09, Vol.13 (3), p.415-422
Main Author:	Hernandez-Prera, Juan C.
Format:	Article
Language:	eng
Subjects:	Adenocarcinoma - classification Adenocarcinoma - history Dentistry Historical Perspectives in Pathology Historical s in Pathology History, 20th Century Humans Medicine Medicine & Public Health Mouth Neoplasms - classification Mouth Neoplasms - history Oral and Maxillofacial Surgery Otorhinolaryngology Pathology
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Summary:	The 2017 World Health Organization Classification of Head and Neck Tumors introduced for the first time the diagnostic terminology “cribriform variant of polymorphous adenocarcinoma”. This nomenclature attempts to reconciliate the ongoing taxonomical controversy related to cribriform adenocarcinoma of tongue. In order to better understand this classification conundrum, it is imperative for pathologist to comprehend the historical evolution of polymorphous adenocarcinoma formerly known as polymorphous “low grade” adenocarcinoma. This review highlights our understanding of these tumors since their origins.
ISSN:	1936-0568 1936-055X 1936-0568