Essential Thrombocythemia: A Case of Acute ST‐Segment Elevation Myocardial Infarction in a Young Female

Essential thrombocythemia (ET) is a clonal disorder of the myeloid stem cell that causes abnormal proliferation of the megakaryocytes. The main feature of the disease is arterial and venous thrombosis caused by platelet dysfunction. Coronary artery involvement leading to acute coronary syndromes is...

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Bibliographic Details
Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2009-02, Vol.32 (2), p.104-105
Main Authors: Bildirici, Ulas, Celikyurt, Umut, Ural, Ertan
Format: Article
Language:English
Subjects:
Adult
Age Factors
Antisickling Agents - therapeutic use
Aspirin - therapeutic use
Biological and medical sciences
Cardiology. Vascular system
Clopidogrel
Coronary Angiography
coronary angioplasty
Coronary heart disease
Diseases of the cardiovascular system
essential thrombocythemia
Female
Fibrinolytic Agents - therapeutic use
Heart
Hematologic and hematopoietic diseases
Heparin - therapeutic use
Humans
Hydroxyurea - therapeutic use
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical sciences
myocardial infarction
Myocardial Infarction - diagnosis
Myocardial Infarction - drug therapy
Myocardial Infarction - etiology
Myocarditis. Cardiomyopathies
Platelet Aggregation Inhibitors - therapeutic use
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Short Communication
Short Communications
Thrombocythemia, Essential - complications
Thrombocythemia, Essential - diagnosis
Ticlopidine - analogs & derivatives
Ticlopidine - therapeutic use
Tirofiban
Tissue Plasminogen Activator - therapeutic use
Tyrosine - analogs & derivatives
Tyrosine - therapeutic use
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Summary:Essential thrombocythemia (ET) is a clonal disorder of the myeloid stem cell that causes abnormal proliferation of the megakaryocytes. The main feature of the disease is arterial and venous thrombosis caused by platelet dysfunction. Coronary artery involvement leading to acute coronary syndromes is a rare complication of the ET. We report a coronary angioplasty and stenting in a 30‐year‐old female patient with acute ST‐segment elevation myocardial infarction (MI) as the first clinical sign of essential thrombocythemia. Facilitated percutaneous coronary intervention with GPIIb/IIIa and/or thrombolytic therapy may be considered as the first treatment modality for this patient group. Copyright © 2009 Wiley Periodicals, Inc.
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.20426