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Rhino-oculo Cerebral Mucormycosis Resistant to Amphotericin B in a Young Patient with Diabetic Ketoacidosis

Rhino-oculo cerebral mucormycosis (ROCM) is a rare, invasive, and rapidly progressive fungal infection affecting nose, paranasal sinuses and often extending to orbit, brain, and palate. The immunocompromised, more commonly patients with diabetes mellitus, fall victim to this lethal form of fungus. A...

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Published in:	Curēus (Palo Alto, CA) CA), 2019-03, Vol.11 (3), p.e4295
Main Authors:	Ali Asghar, Sarrah, Majid, Zainab, Tahir, Faryal, Qadar, Laila Tul, Mir, Saifullah
Format:	Article
Language:	English
Subjects:	Antifungal agents Case reports Diabetes Diabetic ketoacidosis Fungal infections Fungi Health sciences Hemoglobin Infectious Disease Medical imaging Medical prognosis Mortality Neutropenia Nose Other Otolaryngology Patients Quality of life Sinuses Ulcers
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description	Rhino-oculo cerebral mucormycosis (ROCM) is a rare, invasive, and rapidly progressive fungal infection affecting nose, paranasal sinuses and often extending to orbit, brain, and palate. The immunocompromised, more commonly patients with diabetes mellitus, fall victim to this lethal form of fungus. Although the therapeutic approach includes aggressive surgical and medical interventions, ROCM remains a life-threatening infection with poor prognosis. This rare case addresses the outcomes of ROCM in a young patient with delayed diagnosis and resistance to amphotericin B (Ampho B) contributing to dreadful outcomes.
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subjects	Antifungal agents Case reports Diabetes Diabetic ketoacidosis Fungal infections Fungi Health sciences Hemoglobin Infectious Disease Medical imaging Medical prognosis Mortality Neutropenia Nose Other Otolaryngology Patients Quality of life Sinuses Ulcers
title	Rhino-oculo Cerebral Mucormycosis Resistant to Amphotericin B in a Young Patient with Diabetic Ketoacidosis
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