Rhino-oculo Cerebral Mucormycosis Resistant to Amphotericin B in a Young Patient with Diabetic Ketoacidosis

Rhino-oculo cerebral mucormycosis (ROCM) is a rare, invasive, and rapidly progressive fungal infection affecting nose, paranasal sinuses and often extending to orbit, brain, and palate. The immunocompromised, more commonly patients with diabetes mellitus, fall victim to this lethal form of fungus. A...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2019-03, Vol.11 (3), p.e4295
Main Authors: Ali Asghar, Sarrah, Majid, Zainab, Tahir, Faryal, Qadar, Laila Tul, Mir, Saifullah
Format: Article
Language:English
Subjects:
Antifungal agents
Case reports
Diabetes
Diabetic ketoacidosis
Fungal infections
Fungi
Health sciences
Hemoglobin
Infectious Disease
Medical imaging
Medical prognosis
Mortality
Neutropenia
Nose
Other
Otolaryngology
Patients
Quality of life
Sinuses
Ulcers
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Summary:Rhino-oculo cerebral mucormycosis (ROCM) is a rare, invasive, and rapidly progressive fungal infection affecting nose, paranasal sinuses and often extending to orbit, brain, and palate. The immunocompromised, more commonly patients with diabetes mellitus, fall victim to this lethal form of fungus. Although the therapeutic approach includes aggressive surgical and medical interventions, ROCM remains a life-threatening infection with poor prognosis. This rare case addresses the outcomes of ROCM in a young patient with delayed diagnosis and resistance to amphotericin B (Ampho B) contributing to dreadful outcomes.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.4295