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Management of inflammatory rheumatic conditions in the elderly

Abstract The number of elderly people with chronic inflammatory rheumatic diseases is increasing. This heterogeneous and comorbid population is at particular risk of cardiovascular, neoplastic, infectious and iatrogenic complications. The development of biotherapies has paved the way for innovative...

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Bibliographic Details
Published in:Rheumatology (Oxford, England) England), 2019-05, Vol.58 (5), p.748-764
Main Authors: Lahaye, Clément, Tatar, Zuzana, Dubost, Jean-Jacques, Tournadre, Anne, Soubrier, Martin
Format: Article
Language:English
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Summary:Abstract The number of elderly people with chronic inflammatory rheumatic diseases is increasing. This heterogeneous and comorbid population is at particular risk of cardiovascular, neoplastic, infectious and iatrogenic complications. The development of biotherapies has paved the way for innovative therapeutic strategies, which are associated with toxicities. In this review, we have focused on the scientific and therapeutic changes impacting the management of elderly patients affected by RA, SpA or PsA. A multidimensional health assessment resulting in an integrated therapeutic strategy was identified as a major research direction for improving the management of elderly patients.
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/key165