Noninvasive brain stimulation in obsessive-compulsive disorder

Obsessive-compulsive disorder (OCD) is a complex neuropsychiatric disorder with a chronic course, contributing to significant socio-occupational dysfunction. Forty percent of patients remain treatment refractive despite mainstream treatment options such as serotonin-reuptake inhibitors and cognitive...

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Bibliographic Details
Published in:Indian journal of psychiatry 2019-01, Vol.61 (7), p.66-76
Main Authors: Shivakumar, Venkataram, Dinakaran, Damodharan, Narayanaswamy, Janardhanan, Venkatasubramanian, Ganesan
Format: Article
Language:English
Subjects:
Behavior therapy
Brain research
Brain stimulation
Cognition & reasoning
Cognitive ability
Comorbidity
Diagnosis
Magnetic fields
Medical imaging
Mental disorders
Neurobiology
Obsessive compulsive disorder
Review
Serotonin
Studies
Transcranial magnetic stimulation
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Summary:Obsessive-compulsive disorder (OCD) is a complex neuropsychiatric disorder with a chronic course, contributing to significant socio-occupational dysfunction. Forty percent of patients remain treatment refractive despite mainstream treatment options such as serotonin-reuptake inhibitors and cognitive behavior therapy. Noninvasive brain stimulation approaches such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have piqued interest as add-on treatment options in OCD. This review focuses on summarizing the TMS and tDCS studies in OCD with respect to their study design and stimulation parameters and key findings. We also briefly discuss the limitations and future directions noninvasive brain stimulation in OCD.
ISSN:0019-5545
1998-3794
DOI:10.4103/psychiatry.IndianJPsychiatry_522_18