The Effect of Nutrient Supplementation in Management of Polycystic Ovary Syndrome Associated Metabolic Dysfunctions: A Critical Review

Polycystic ovary syndrome (PCOS) is complex heterogeneous disorder that has several aspects in terms of pathology such as metabolic, endocrine, reproductive, and psychological. However, the etiology of PCOS remains poorly understood. Several studies suggest that insulin resistance and hyperandrogeni...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the Turkish German Gynecological Association 2018-12, Vol.19 (4), p.220-232
Main Authors: Günalan, Elif, Yaba, Aylin, Yılmaz, Bayram
Format: Article
Language:English
Subjects:
Acne
Androgens
Dietary supplements
Fatty acids
Infertility
Insulin resistance
Lipids
Metabolism
Metabolites
Microbiota
Nutrients
Nutrition
Obesity
Pathogenesis
Plasma
Polycystic ovary syndrome
Probiotics
Proteins
Review
Systematic review
Tıp
Vitamin B
Weight control
Womens health
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Polycystic ovary syndrome (PCOS) is complex heterogeneous disorder that has several aspects in terms of pathology such as metabolic, endocrine, reproductive, and psychological. However, the etiology of PCOS remains poorly understood. Several studies suggest that insulin resistance and hyperandrogenism play a central role in the progression of PCOS pathophysiology. Therefore, common treatment strategies of PCOS are based on lifestyle modification, which include exercise, diet, and nutrient supplementation therapy. Recent studies have recommended some nutrients such as vitamins, minerals, and vitamin-like nutrients for the therapy of PCOS because each has at least one functional property in PCOS-induced pathways. Therefore, it is claimed that the cause of PCOS could be vitamin or mineral deficiency. This review aims to provide a critical literature survey on nutritional supplementation for the treatment of PCOS-associated endocrine and metabolic dysfunctions and discuss the role of nutrients in the management of PCOS in view of the clinical trials and experimental studies. (J Turk Ger Gynecol Assoc 2018; 19: 220-32)
ISSN:1309-0399
1309-0380
DOI:10.4274/jtgga.2018.0077