Safety of coronary CT angiography and functional testing for stable chest pain in the PROMISE trial: A randomized comparison of test complications, incidental findings, and radiation dose

Coronary computed tomography angiography (CTA) and functional testing strategies for stable chest pain yield similar outcomes; one aspect that may guide test choice is safety. We compared test safety (test complications, incidental findings, and effective radiation dose) between CTA and functional t...

Full description

Saved in:
Bibliographic Details
Published in:Journal of cardiovascular computed tomography 2017-09, Vol.11 (5), p.373-382
Main Authors: Lu, Michael T., Douglas, Pamela S., Udelson, James E., Adami, Elizabeth, Ghoshhajra, Brian B., Picard, Michael H., Roberts, Rhonda, Lee, Kerry L., Einstein, Andrew J., Mark, Daniel B., Velazquez, Eric J., Carter, William, Ridner, Michael, Al-Khalidi, Hussein R., Hoffmann, Udo
Format: Article
Language:English
Subjects:
Aged
Angina Pectoris - diagnostic imaging
Angina Pectoris - etiology
Chest pain
Computed Tomography Angiography - adverse effects
Coronary Angiography - adverse effects
Coronary Angiography - methods
Coronary artery disease
Coronary Artery Disease - complications
Coronary Artery Disease - diagnostic imaging
Coronary computed tomography angiography
Coronary Stenosis - complications
Coronary Stenosis - diagnostic imaging
Echocardiography, Stress - adverse effects
Female
Functional testing
Humans
Incidental Findings
Male
Middle Aged
Multidetector Computed Tomography - adverse effects
North America
Predictive Value of Tests
Prospective Studies
Radiation Dosage
Radiation Exposure
Radionuclide Imaging - adverse effects
Risk Assessment
Risk Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Coronary computed tomography angiography (CTA) and functional testing strategies for stable chest pain yield similar outcomes; one aspect that may guide test choice is safety. We compared test safety (test complications, incidental findings, and effective radiation dose) between CTA and functional testing as-tested in PROMISE (PROspective Multicenter Imaging Study for Evaluation of Chest Pain). In the subgroup whose physicians intended nuclear stress over other functional tests if randomized to the functional arm, we compared radiation dose of CTA versus nuclear stress and identified characteristics associated with dose. Of 9470 patients, none had major and
ISSN:1934-5925
1876-861X
DOI:10.1016/j.jcct.2017.08.005