Obesity: the 'huge' problem in cardiovascular diseases

Obesity is an epidemic in the United States. It is an independent risk factor for cardiovascular diseases and associated with reduced life expectancy. The adverse effects are related to direct impact of obesity on cardiovascular system and indirectly through its influence on risk factors. Excessive...

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Bibliographic Details
Published in:Missouri medicine 2013-11, Vol.110 (6), p.499-504
Main Authors: Ashraf, M Javed, Baweja, Paramdeep
Format: Article
Language:English
Subjects:
Adipokines - metabolism
Adipose Tissue - secretion
Cardiovascular Diseases - complications
Cardiovascular Diseases - metabolism
Cardiovascular Diseases - therapy
Coronary Disease - complications
Coronary Disease - metabolism
Coronary Disease - therapy
Death, Sudden, Cardiac
Diabetes Complications
Diabetes Mellitus - metabolism
Diabetes Mellitus - therapy
Dyslipidemias - complications
Dyslipidemias - metabolism
Dyslipidemias - therapy
Exercise
Heart Failure - complications
Heart Failure - metabolism
Heart Failure - therapy
Humans
Hypertension - complications
Hypertension - metabolism
Hypertension - therapy
Inflammation - metabolism
Obesity - complications
Obesity - metabolism
Obesity - therapy
Overweight - complications
Overweight - metabolism
Overweight - therapy
Science of Medicine
United States
Weight Reduction Programs
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Summary:Obesity is an epidemic in the United States. It is an independent risk factor for cardiovascular diseases and associated with reduced life expectancy. The adverse effects are related to direct impact of obesity on cardiovascular system and indirectly through its influence on risk factors. Excessive accumulation of adipose tissue in the myocardium leads to structural and functional alteration. In addition, numerous hormones secreted by adipose tissue create pro-inflammatory and prothrombotic state. This predisposes to coronary heart disease, heart failure, and sudden death. Even those with normal weight but excessive body fat are at risk. Weight reduction and exercise are the main therapeutic options.
ISSN:0026-6620