Suspect Screening Analysis of Chemicals in Consumer Products

A two-dimensional gas chromatography-time-of-flight/mass spectrometry (GC×GC-TOF/MS) suspect screening analysis method was used to rapidly characterize chemicals in 100 consumer productswhich included formulations (e.g., shampoos, paints), articles (e.g., upholsteries, shower curtains), and foods (...

Full description

Saved in:
Bibliographic Details
Published in:Environmental science & technology 2018-03, Vol.52 (5), p.3125-3135
Main Authors: Phillips, Katherine A, Yau, Alice, Favela, Kristin A, Isaacs, Kristin K, McEachran, Andrew, Grulke, Christopher, Richard, Ann M, Williams, Antony J, Sobus, Jon R, Thomas, Russell S, Wambaugh, John F
Format: Article
Language:English
Subjects:
Cereals
Chemicals
Consumer goods
Consumer products
Curtains
Environmental health
Food
Formulations
Gas chromatography
Health risk assessment
Health risks
Human exposure
Mass spectrometry
Mass spectroscopy
Screening
Shampoos
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A two-dimensional gas chromatography-time-of-flight/mass spectrometry (GC×GC-TOF/MS) suspect screening analysis method was used to rapidly characterize chemicals in 100 consumer productswhich included formulations (e.g., shampoos, paints), articles (e.g., upholsteries, shower curtains), and foods (cereals)and therefore supports broader efforts to prioritize chemicals based on potential human health risks. Analyses yielded 4270 unique chemical signatures across the products, with 1602 signatures tentatively identified using the National Institute of Standards and Technology 2008 spectral database. Chemical standards confirmed the presence of 119 compounds. Of the 1602 tentatively identified chemicals, 1404 were not present in a public database of known consumer product chemicals. Reported data and model predictions of chemical functional use were applied to evaluate the tentative chemical identifications. Estimated chemical concentrations were compared to manufacturer-reported values and other measured data. Chemical presence and concentration data can now be used to improve estimates of chemical exposure, and refine estimates of risk posed to human health and the environment.
ISSN:0013-936X
1520-5851
DOI:10.1021/acs.est.7b04781