Ocular changes over 60 min in supine and prone postures

Some astronauts are returning from long-duration spaceflight with structural ocular and visual changes. We investigated both the transient and sustained effects of changes in the direction of the gravity vector acting on the eye using changes in body posture. Intraocular pressure (IOP; measured by P...

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Bibliographic Details
Published in:Journal of applied physiology (1985) 2017-08, Vol.123 (2), p.415-423
Main Authors: Anderson, Allison P, Babu, Gautam, Swan, Jacob G, Phillips, Scott D, Knaus, Darin A, Toutain-Kidd, Christine M, Zegans, Michael E, Fellows, Abigail M, Gui, Jiang, Buckey, Jay C
Format: Article
Language:English
Subjects:
Adult
Astronauts
Blood Pressure - physiology
Choroid - physiology
Cornea
Covariance
Eye
Female
Females
Geometry
Gravitation
Gravity
Humans
Intraocular pressure
Intraocular Pressure - physiology
Long duration space flight
Male
Males
Optical Coherence Tomography
Posture
Posture - physiology
Prone position
Prone Position - physiology
Space flight
Supine position
Tomography, Optical Coherence - methods
Tonometry, Ocular - methods
Weightlessness
Young Adult
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Summary:Some astronauts are returning from long-duration spaceflight with structural ocular and visual changes. We investigated both the transient and sustained effects of changes in the direction of the gravity vector acting on the eye using changes in body posture. Intraocular pressure (IOP; measured by Perkins tonometer), ocular geometry (axial length, corneal thickness, and aqueous depth-noncontact biometer), and the choroid (volume and subfoveal thickness optical coherence tomography) were measured in 10 subjects (5 males and 5 females). Measures were taken over the course of 60 min and analyzed with repeated-measures analysis of covariance to assess the effects of posture and time. In the supine position, choroidal volume increased significantly with time (average value at
ISSN:8750-7587
1522-1601
DOI:10.1152/japplphysiol.00687.2016