Fungal keratitis caused by a rare ocular pathogen, Gjaerumia minor: A case report

Fungal keratitis is an important infection of the eye that may cause devastating effects. Keratitis caused by fungi has been described in many parts of the world mainly in tropical countries. The objective of this study is to report a serious eye infection in an adult with a known history of diabete...

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Bibliographic Details
Published in:Saudi journal of ophthalmology 2018-04, Vol.32 (2), p.160-163
Main Authors: Al-Falki, Yahya H., Alshehri, Mohamed A., Joseph, Martin R.P., Hamid, Mohamed E.
Format: Article
Language:English
Subjects:
Case Report
Corneal scraping
Fungal keratitis
Georgefischeriales
Large subunit ribosomal RNA
Oculomycosis
Tilletiopsis minor
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Summary:Fungal keratitis is an important infection of the eye that may cause devastating effects. Keratitis caused by fungi has been described in many parts of the world mainly in tropical countries. The objective of this study is to report a serious eye infection in an adult with a known history of diabetes caused by an uncommon yeast fungus with details of clinical findings and laboratory investigations. Left eye visual acuity was no perception of light due to end stage neovascular glaucoma. The patient was pseudophakic in both eyes. Culture of a corneal scraping showed yeast like organism on Sabouraud dextrose agar. Gjaerumia minor, a rare yeast but with history of a pulmonary infection in the region, was confirmed with 98% similarity in the large subunit ribosomal RNA gene (accession KY690175). Topical Amphotericin B and oral fluconazole were initiated. The patient showed gradual improvement, epithelial defect healed, infiltration steadily regressed and hypopyon disappeared. We report the first case of fungal keratitis caused by G. minor in Saudi Arabia. Fungal Keratitis should be considered in cases where clinical response to the conventional antibacterial antibiotic treatment is not optimal.
ISSN:1319-4534
DOI:10.1016/j.sjopt.2017.09.007