Control networks and hubs

Executive control functions are associated with frontal, parietal, cingulate, and insular brain regions that interact through distributed large‐scale networks. Here, we discuss how fMRI functional connectivity can shed light on the organization of control networks and how they interact with other pa...

Full description

Saved in:
Bibliographic Details
Published in:Psychophysiology 2018-03, Vol.55 (3), p.n/a
Main Authors: Gratton, Caterina, Sun, Haoxin, Petersen, Steven E.
Format: Article
Language:English
Subjects:
Brain
Brain mapping
cognitive control
Control systems
executive control
Executive function
fMRI
functional connectivity
Functional magnetic resonance imaging
networks
Neural networks
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Executive control functions are associated with frontal, parietal, cingulate, and insular brain regions that interact through distributed large‐scale networks. Here, we discuss how fMRI functional connectivity can shed light on the organization of control networks and how they interact with other parts of the brain. In the first section of our review, we present convergent evidence from fMRI functional connectivity, activation, and lesion studies that there are multiple dissociable control networks in the brain with distinct functional properties. In the second section, we discuss how graph theoretical concepts can help illuminate the mechanisms by which control networks interact with other brain regions to carry out goal‐directed functions, focusing on the role of specialized hub regions for mediating cross‐network interactions. Again, we use a combination of functional connectivity, lesion, and task activation studies to bolster this claim. We conclude that a large‐scale network perspective provides important neurobiological constraints on the neural underpinnings of executive control, which will guide future basic and translational research into executive function and its disruption in disease.
ISSN:0048-5772
1469-8986
1540-5958
DOI:10.1111/psyp.13032