Specimen mapping in head and neck cancer using fluorescence imaging

Overview Although the agreed‐upon standard is circumferential pathology analysis of the interface between the resected specimen and the patient, there is currently no consensus on the optimal methodology to achieve this in head and neck cancer specimens. This is most commonly conducted by either sam...

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Bibliographic Details
Published in:Laryngoscope Investigative Otolaryngology 2017-12, Vol.2 (6), p.447-452
Main Authors: Teraphongphom, Nutte, Kong, Christina S., Warram, Jason M., Rosenthal, Eben L.
Format: Article
Language:English
Subjects:
Accuracy
Clinical trials
Communication
fluorescence
General Otolaryngology
Head & neck cancer
image‐guidance
oncology
Pathology
probes
Surgery
Surgical outcomes
Tumors
Vascular endothelial growth factor
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Summary:Overview Although the agreed‐upon standard is circumferential pathology analysis of the interface between the resected specimen and the patient, there is currently no consensus on the optimal methodology to achieve this in head and neck cancer specimens. This is most commonly conducted by either sampling the wound bed after resection or obtaining samples from the specimen. Regardless of the technique, only a fraction of the area of interest can be sampled due to the labor‐intensive nature of frozen sections. Objective This review will cover and define the possible role for optical mapping of the surgical specimen using fluorescence imaging in head and neck cancer. Level of Evidence NA
ISSN:2378-8038
0023-852X
2378-8038
DOI:10.1002/lio2.84