Evidence for altered levels of Immunoglobulin D in the nasal airway mucosa of patients with chronic rhinosinusitis

Abstract Background Immunoglobulin D (IgD) is an enigmatic antibody isotype best known when co-expressed with IgM on naïve B cells. However, elevated soluble IgD (sIgD) and increased IgD+ IgM- B cell populations have been described in the human upper respiratory mucosa. Objective We assessed whether...

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Bibliographic Details

Published in:	Journal of allergy and clinical immunology 2017-06, Vol.140 (6), p.1562-1571.e5
Main Authors:	Min, Jin-Young, MD, PhD, Nayak, Jayakar V., MD, PhD, Hulse, Kathryn E., PhD, Stevens, Whitney W., MD, PhD, Raju, Paul A., PhD, Huang, Julia H., MS, Suh, Lydia A., BS, Van Roey, Griet A., PhD, Norton, James E., MS, Carter, Roderick G., BS, Price, Caroline P.E., BA, Weibman, Ava R., BA, Rashan, Ali R., MD, Ghosn, Eliver E., PhD, Patel, Zara M., MD, Homma, Tetsuya, MD, PhD, Conley, David B., MD, Welch, Kevin C., MD, Shintani-Smith, Stephanie, MD, MS, Peters, Anju T., MD, Grammer, Leslie C., MD, Harris, Kathleen E., BS, Kato, Atsushi, PhD, Hwang, Peter H., MD, Kern, Robert C., MD, Herzenberg, Leonore A., PhD, Schleimer, Robert P., PhD, Tan, Bruce K., MD, MS
Format:	Article
Language:	English
Subjects:	Allergy and Immunology
Online Access:	Get full text
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