Multifunctional Albumin Nanoparticles As Combination Drug Carriers for Intra-Tumoral Chemotherapy

Current cancer therapies are challenged by weakly soluble drugs and by drug combinations that exhibit non‐uniform biodistribution and poor bioavailability. In this study, we have presented a new platform of advanced healthcare materials based on albumin nanoparticles (ANPs) engineered as tumor penet...

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Bibliographic Details

Published in:	Advanced healthcare materials 2013-09, Vol.2 (9), p.1236-1245
Main Authors:	Cui, Mingjie, Naczynski, Dominik J., Zevon, Margot, Griffith, Craig K., Sheihet, Larisa, Poventud-Fuentes, Izmarie, Chen, Suzie, Roth, Charles M., Moghe, Prabhas V.
Format:	Article
Language:	eng
Subjects:	albumin nanoparticles Albumins Antineoplastic Agents - administration & dosage Antineoplastic Agents - chemistry Antineoplastic Agents - toxicity Cancer Cell Line, Tumor Cell Survival - drug effects collagenase Collagenases - metabolism Combinatorial analysis Curcumin - administration & dosage Curcumin - chemistry Curcumin - toxicity Cytotoxicity Drug Carriers - chemistry drug delivery Drug therapy Drugs Humans Melanoma Nanoparticles Nanoparticles - chemistry Nanoparticles - ultrastructure Neoplasms - drug therapy Particle Size Recombinant Proteins - biosynthesis Recombinant Proteins - chemistry Recombinant Proteins - genetics Riluzole - administration & dosage Riluzole - chemistry Riluzole - toxicity Serum Albumin - chemistry Serum Albumin - genetics Serum Albumin - metabolism Spheroids tumor penetration Tumors Uptakes
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