Spinal cord ependymoma: a review of the literature and case series of ten patients

Spinal cord ependymoma: a review of the literature and case series of ten patients

Spinal cord ependymoma (SCE) is a rare tumor that is most commonly low-grade. Complete surgical resection has been established as first-line treatment and can be curative. However, SCEs tend to recur when complete tumor resection is not possible. Evidence supporting the use of adjuvant radiation and...

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Bibliographic Details
Published in:Journal of Neuro - Oncology 2016-07, Vol.128 (3), p.377-386
Main Authors: Celano, Emma, Salehani, Arsalaan, Malcolm, James G., Reinertsen, Erik, Hadjipanayis, Constantinos G.
Format: Article
Language:eng
Subjects:
Adult
Cohort Studies
Ependymoma - diagnosis
Ependymoma - genetics
Ependymoma - pathology
Ependymoma - therapy
Female
Follow-Up Studies
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Neurology
Oncology
Spinal Cord - diagnostic imaging
Spinal Cord - pathology
Spinal Cord - surgery
Spinal Cord Neoplasms - diagnosis
Spinal Cord Neoplasms - genetics
Spinal Cord Neoplasms - pathology
Spinal Cord Neoplasms - therapy
Topic Review
Young Adult
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Description
Summary:Spinal cord ependymoma (SCE) is a rare tumor that is most commonly low-grade. Complete surgical resection has been established as first-line treatment and can be curative. However, SCEs tend to recur when complete tumor resection is not possible. Evidence supporting the use of adjuvant radiation and chemotherapy is not definitive. We review the most recent literature on SCE covering a comprehensive range of topics spanning the biology, presentation, clinical management, and outcomes. In addition, we present a case series of ten SCE patients with the goal of contributing to existing knowledge of this rare disease.
ISSN:0167-594X
1573-7373