Hepatic Venous Pressure Gradient Measurement in Bangladeshi Cirrhotic Patients: A Correlation with Child's Status, Variceal Size, and Bleeding

Hepatic venous pressure gradient (HVPG) reflects the portal pressure in patients with cirrhotic portal hypertension. The aim of the study was to assess the relation of HVPG to variceal size, Child-Pugh status, and variceal bleeding. A total of 96 patients with cirrhosis of liver were enrolled prospe...

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Published in:Euroasian journal of hepato-gastroenterology 2017-07, Vol.7 (2), p.142-145
Main Authors: Al Mahtab, Mamun, M Noor E Alam, Sheikh, A Rahim, Mohammad, A Alam, Mohammad, A Khondaker, Faiz, L Moben, Ahmed, Mohsena, Masuda, Mohammad Fazle Akbar, Sheikh
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Language:English
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Summary:Hepatic venous pressure gradient (HVPG) reflects the portal pressure in patients with cirrhotic portal hypertension. The aim of the study was to assess the relation of HVPG to variceal size, Child-Pugh status, and variceal bleeding. A total of 96 patients with cirrhosis of liver were enrolled prospectively and each patient's HVPG level was measured via the transfemoral route. Clinical and biochemical evaluation and upper gastrointestinal (GI) endoscopy were done in each subject. Severity of cirrhosis was assessed by Child's status. The mean HVPG was higher in patients with Child's B and C (14.10 ± 7.56 and 13.64 ± 7.17 mm Hg respectively) compared with those of Child's A (10.15 ± 5.63 mm Hg). The levels of HVPG differed significantly between Child's classes A and B (p = 0.011) and Child's A and C (p = 0.041). The mean HVPG was also higher in bleeders compared with nonbleeders with large varices (17.7 ± 5.5 14.9 ± 4.7 mmHg respectively; p = 0.006). Hepatic venous pressure gradient seems to be important to assess the severity of liver cirrhosis. Al Mahtab M, Noor E Alam SM, Rahim MA, Alam MA, Khondaker FA, Moben AL, Mohsena M, Akbar SMF. Hepatic Venous Pressure Gradient Measurement in Bangladeshi Cirrhotic Patients: A Correlation with Child's Status, Variceal Size, and Bleeding. Euroasian J Hepato-Gastroenterol 2017;7(2):142-145.
ISSN:2231-5047
2231-5128
DOI:10.5005/jp-journals-10018-1235