Quantifying Postdonation Risk of ESRD in Living Kidney Donors

Studies have estimated the average risk of postdonation ESRD for living kidney donors in the United States, but personalized estimation on the basis of donor characteristics remains unavailable. We studied 133,824 living kidney donors from 1987 to 2015, as reported to the Organ Procurement and Trans...

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Bibliographic Details
Published in:Journal of the American Society of Nephrology 2017-09, Vol.28 (9), p.2749-2755
Main Authors: Massie, Allan B, Muzaale, Abimereki D, Luo, Xun, Chow, Eric K H, Locke, Jayme E, Nguyen, Anh Q, Henderson, Macey L, Snyder, Jon J, Segev, Dorry L
Format: Article
Language:English
Subjects:
Adult
Age Factors
Black or African American - statistics & numerical data
Body Mass Index
Clinical Research
Female
Humans
Incidence
Kidney Failure, Chronic - epidemiology
Kidney Failure, Chronic - ethnology
Kidney Transplantation
Living Donors - statistics & numerical data
Male
Middle Aged
Risk Assessment
Risk Factors
Sex Factors
United States - epidemiology
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Summary:Studies have estimated the average risk of postdonation ESRD for living kidney donors in the United States, but personalized estimation on the basis of donor characteristics remains unavailable. We studied 133,824 living kidney donors from 1987 to 2015, as reported to the Organ Procurement and Transplantation Network, with ESRD ascertainment Centers for Medicare and Medicaid Services linkage, using Cox regression with late entries. Black race (hazard ratio [HR], 2.96; 95% confidence interval [95% CI], 2.25 to 3.89;
ISSN:1046-6673
1533-3450
DOI:10.1681/ASN.2016101084