The prevalence and risk factors associated with osteoradionecrosis of the jaw in oral and oropharyngeal cancer patients treated with intensity-modulated radiation therapy (IMRT): The Memorial Sloan Kettering Cancer Center experience

Highlights • The prevalence of ORN in OCC & OPC patients treated with IMRT is 4.3%. • OPC patients are prone to develop ORN earlier compared to OCC patients. • High radiation dose, poor periodontal status and alcohol use are associated with ORN.

Saved in:
Bibliographic Details
Published in:Oral oncology 2017-01, Vol.64, p.44-51
Main Authors: Owosho, Adepitan A, Tsai, C. Jillian, Lee, Ryan S, Freymiller, Haley, Kadempour, Arvin, Varthis, Spyridon, Sax, Adi Z, Rosen, Evan B, Yom, SaeHee K, Randazzo, Joseph, Drill, Esther, Riedel, Elyn, Patel, Snehal, Lee, Nancy Y, Huryn, Joseph M, Estilo, Cherry L
Format: Article
Language:English
Subjects:
Adult
Aged
Female
Head and neck cancer
Hematology, Oncology and Palliative Medicine
Humans
Intensity-modulated radiation therapy
Jaw Diseases - etiology
Male
Middle Aged
Mouth Neoplasms - radiotherapy
Oral cancer
Oropharyngeal cancer
Oropharyngeal Neoplasms - radiotherapy
Osteoradionecrosis
Osteoradionecrosis - etiology
Otolaryngology
Prevalence
Radiotherapy, Intensity-Modulated - adverse effects
Retrospective Studies
Risk Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • The prevalence of ORN in OCC & OPC patients treated with IMRT is 4.3%. • OPC patients are prone to develop ORN earlier compared to OCC patients. • High radiation dose, poor periodontal status and alcohol use are associated with ORN.
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2016.11.015