Impressions of pharmacogenomic testing among Certified Registered Nurse Anesthetists: a mixed-method study

Pharmacogenomic testing is useful in helping to predict and explain patient responsiveness to medication. In clinical practice, the use of pharmacogenomic testing has been shown to help reduce adverse drugs events and increase patient satisfaction with their healthcare. Prior to a test being useful,...

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Bibliographic Details
Published in:Pharmacogenomics 2016-04, Vol.17 (6), p.593-602
Main Authors: Riddle, Dru, Gregoski, Mat, Baker, Kathy, Dumas, Bonnie, Jenkins, Carolyn H
Format: Article
Language:English
Subjects:
Anesthesia
Anesthesiology - methods
Attitude of Health Personnel
Clinical medicine
clinical utility
Data analysis
Decision making
Disease control
Drug-Related Side Effects and Adverse Reactions - prevention & control
Ethics
factor analysis
Female
Generalized linear models
Genomics
Humans
Interviews
Male
Metabolism
Methods
Middle Aged
Mixed methods research
mixed-method
Nurse Anesthetists - psychology
Nurse specialists
Pain
Perceptions
pharmacogenomic testing
Pharmacogenomic Testing - methods
Pharmacogenomics
Primary care
Public health
Social impact
Social sciences
Software
Surveys and Questionnaires
Validity
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Summary:Pharmacogenomic testing is useful in helping to predict and explain patient responsiveness to medication. In clinical practice, the use of pharmacogenomic testing has been shown to help reduce adverse drugs events and increase patient satisfaction with their healthcare. Prior to a test being useful, it must have clinical utility. There is a gap in the literature about the perceived clinical utility of pharmacogenomic testing among anesthesia providers. This qualitative-quantitative sequential mixed-method study used focused interviews to formulate probes for a quantitative survey aimed at quantifying the perceptions of anesthesia providers about pharmacogenomic testing. The results indicate anesthesia providers do not have enough knowledge about pharmacogenomic testing for it to be considered clinically useful in anesthesia practice. Although outcomes data indicate pharmacogenomic testing can help predict outcomes, anesthesia providers do not have enough knowledge and have concerns about the ethical implications of pharmacogenomic testing.
ISSN:1462-2416
1744-8042
DOI:10.2217/pgs.16.3