Does surgical delay for radical prostatectomy affect patient pathological outcome? A retrospective analysis from a Canadian cohort

We sought to assess the impact of surgical wait time (SWT) to robot-assisted radical prostatectomy (RARP) on final pathological outcome. A retrospective review of RARP patient records operated between 2006 and 2015 was conducted. SWT was defined as period from prostate biopsy to surgery. Primary out...

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Published in:Canadian Urological Association journal 2017-08, Vol.11 (8), p.265-9
Main Authors: Zanaty, Marc, Alnazari, Mansour, Lawson, Kelsey, Azizi, Mounsif, Rajih, Emad, Alenizi, Abdullah, Hueber, Pierre-Alain, Meskawi, Malek, Lebacle, Cedric, Lebeau, Thierry, Benayoun, Serge, Karakiewicz, Pierre I, El-Hakim, Assaad, Zorn, Kevin C
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Language:English
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Summary:We sought to assess the impact of surgical wait time (SWT) to robot-assisted radical prostatectomy (RARP) on final pathological outcome. A retrospective review of RARP patient records operated between 2006 and 2015 was conducted. SWT was defined as period from prostate biopsy to surgery. Primary outcome was the impact on postoperative Cancer of the Prostate Risk Assessment (CAPRA-S) score. Patients were stratified according to D'Amico risk categories. Univariate analysis (UVA) and multivariable (MVA) analysis with a generalized linear model was used to evaluate the effect of SWT and other predictive factors on pathological outcome in individual risk group and on the overall sample. A total of 835 patients were eligible for analysis. Mean SWT was significantly different between the three D'Amico groups, with mean SWT of 180.22 days (95% confidence interval [CI] 169.03; 191.41), 159.14 days (95% CI 152.38; 165.90), and 138.96 days (95% CI 124.60; 153.33) for low-, intermediate-, and high-risk groups, respectively (p
ISSN:1911-6470
1920-1214
DOI:10.5489/cuaj.4149