Impact and prognostic value of 18F-fluorodeoxyglucose positron emission tomography-computed tomography scan in the evaluation of residual head and neck cancer: Single-center experience from Pakistan

Abstract Background: Overview of clinical impact of positron emission tomography-computed tomography (PET-CT) scans in patients with head and neck carcinomas at our center. Methods: Retrospective review of posttreatment 18 F-fluorodeoxyglucose ( 18 F-FDG) PET-CT scans in patients with head and neck...

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Bibliographic Details
Published in:South Asian Journal of Cancer 2017-04, Vol.6 (2), p.081-083
Main Authors: Riaz, Saima, Bashir, Humayun, Iqbal, Hassan, Jamshed, Arif, Murtaza, Ahmad, Hussain, Raza
Format: Article
Language:English
Subjects:
18F-fluorodeoxyglucose positron emission tomography-computed tomography scan
disease-free survival
head and neck cancer
maximum standardized uptake values
ORIGINAL ARTICLE : SAARC Selection
squamous cell carcinoma
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Summary:Abstract Background: Overview of clinical impact of positron emission tomography-computed tomography (PET-CT) scans in patients with head and neck carcinomas at our center. Methods: Retrospective review of posttreatment 18 F-fluorodeoxyglucose ( 18 F-FDG) PET-CT scans in patients with head and neck carcinomas with risk of residual disease. Clinical outcome served as the reference standard. Results: This study included 93 patients (65.6% males, mean age: 48.8 years ± 17.2 standard deviation) with squamous cell carcinoma as most frequent histopathology (91.4%). PET-CT scans were performed on average 6 months posttreatment. Diagnostic accuracy, positive predictive value, and negative predictive value of PET-CT for disease were found to be 88%, 88%, and 92%, respectively. A median follow-up of 24 months was available for 91 patients. Kaplan–Meier curves showed significantly higher disease-free survival with negative PET-CT as compared to positive PET-CT (P = 0.01) and maximum standardized uptake values of
ISSN:2278-330X
2278-4306
DOI:10.4103/2278-330X.208851