Spatial Analysis of Air Pollution and Mortality in California

Although substantial scientific evidence suggests that chronic exposure to ambient air pollution contributes to premature mortality, uncertainties exist in the size and consistency of this association. Uncertainty may arise from inaccurate exposure assessment. To assess the associations of three typ...

Full description

Saved in:
Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2013-09, Vol.188 (5), p.593-599
Main Authors: JERRETT, Michael, BURNETT, Richard T, GAPSTUR, Susan M, THUN, Michael J, ARDEN POPE, C, BECKERMAN, Bernardo S, TURNER, Michelle C, KREWSKI, Daniel, THURSTON, George, MARTIN, Randall V, VAN DONKELAAR, Aaron, HUGHES, Edward, YUANLI SHI
Format: Article
Language:English
Subjects:
Air Pollutants - adverse effects
Air pollution
Air Pollution - adverse effects
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
California - epidemiology
Cancer
Environment. Living conditions
Environmental Exposure - adverse effects
Environmental Exposure - statistics & numerical data
Female
Humans
Intensive care medicine
Land use
Male
Medical sciences
Middle Aged
Mortality
Nitrogen dioxide
Nitrogen Dioxide - adverse effects
Outdoor air quality
Ozone - adverse effects
Particulate Matter - adverse effects
Pneumology
Pollutants
Postal codes
Proportional Hazards Models
Public health. Hygiene
Public health. Hygiene-occupational medicine
Regression Analysis
Risk Factors
Survival Analysis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Although substantial scientific evidence suggests that chronic exposure to ambient air pollution contributes to premature mortality, uncertainties exist in the size and consistency of this association. Uncertainty may arise from inaccurate exposure assessment. To assess the associations of three types of air pollutants (fine particulate matter, ozone [O3], and nitrogen dioxide [NO2]) with the risk of mortality in a large cohort of California adults using individualized exposure assessments. For fine particulate matter and NO2, we used land use regression models to derive predicted individualized exposure at the home address. For O3, we estimated exposure with an inverse distance weighting interpolation. Standard and multilevel Cox survival models were used to assess the association between air pollution and mortality. Data for 73,711 subjects who resided in California were abstracted from the American Cancer Society Cancer Prevention II Study cohort, with baseline ascertainment of individual characteristics in 1982 and follow-up of vital status through to 2000. Exposure data were derived from government monitors. Exposure to fine particulate matter, O3, and NO2 was positively associated with ischemic heart disease mortality. NO2 (a marker for traffic pollution) and fine particulate matter were also associated with mortality from all causes combined. Only NO2 had significant positive association with lung cancer mortality. Using the first individualized exposure assignments in this important cohort, we found positive associations of fine particulate matter, O3, and NO2 with mortality. The positive associations of NO2 suggest that traffic pollution relates to premature death.
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.201303-0609OC