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PROTECTIVE ROLE OF CARNITINE SYNERGIZED WITH VITAMIN E AGAINST ISOPROTERENOL INDUCED CARDIAC INFARCTION IN RATS
The current study aimed to evaluate the role of carnitine in combination with vitamin E in protection against myocardial infarction induced by isoproterenol (ISO) in rats. Rats were grouped into 5 (each 10 rats): Group I. Control fed a standard diet. Group III: Rats were injected with vitamin E (100...
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Published in: | African journal of traditional, complementary, and alternative medicines complementary, and alternative medicines, 2017, Vol.14 (2), p.25-32 |
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Main Authors: | , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that cite this one |
Online Access: | Get full text |
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Summary: | The current study aimed to evaluate the role of carnitine in combination with vitamin E in protection against myocardial infarction induced by isoproterenol (ISO) in rats.
Rats were grouped into 5 (each 10 rats): Group I. Control fed a standard diet. Group III: Rats were injected with vitamin E (100 IU/kg bw, i.p) daily. Group IV: Rats were given carnitine (20 mg/kg bw, i.p) daily. Group V: Rats were injected with both vitamin E (100 IU/kg bw,
and carnitine (20 mg/kg bw,
daily. On 7
, 8
, and 9
day, rats in groups (II-V) were injection
with ISO (55mg/kg b.w for successive three days). The treatment with carnitine and vitamin E were continuous for 21 days.
Canirine combined with vitamin E significantly increased coronary flow (CF) (P |
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ISSN: | 0189-6016 2505-0044 |
DOI: | 10.21010/ajtcam.v14i2.4 |