The Antigastric Cancer Activity of San Leng Powder Extract Induces Apoptosis in Balb/C Bearing-SGC-7901 Mice

The Antigastric Cancer Activity of San Leng Powder Extract Induces Apoptosis in Balb/C Bearing-SGC-7901 Mice

San Leng powder extract has been used as medicinal compound for the prevention and treatment of cancers. The antitumor activity of SLPE was determined by treating BALB/C mice harboring a human gastric cancer xenograft with SPLE for 17 days. Mice were also treated with fluorouracil (5-Fu, 25 mg/kg) o...

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Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2017-01, Vol.2017, p.1052125-11
Main Authors: Yu, Chen, Ji, Ai-Jun, Lu, Jian-Wei, Liu, Shi-Jia, Sun, Yu
Format: Article
Language:eng
Subjects:
Apoptosis
Cancer therapies
Care and treatment
Cell cycle
Cell growth
Chemical properties
Chemotherapy
Chinese medicine
Chromatography
Commelinids
Health aspects
Hospitals
Materia medica, Vegetable
Medical research
Medicine, Botanic
Medicine, Chinese
Medicine, Herbal
Methods
Plant extracts
Rodents
Signal transduction
Stomach cancer
Tumors
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Summary:San Leng powder extract has been used as medicinal compound for the prevention and treatment of cancers. The antitumor activity of SLPE was determined by treating BALB/C mice harboring a human gastric cancer xenograft with SPLE for 17 days. Mice were also treated with fluorouracil (5-Fu, 25 mg/kg) or a combination of SLPE and 5-Fu. Our results indicate that the inhibition of tumor growth by SLPE might be due to a block in the cell cycle and the induction of apoptosis. These results suggest that SLPE might be useful in the treatment of gastric cancer.
ISSN:1741-427X
1741-4288