Safety and Patient Satisfaction of AbobotulinumtoxinA for Aesthetic Use: A Systematic Review

A systematic review of the published literature (from January 2000 to January 2016) to ascertain the safety of, and patient satisfaction with, the aesthetic use of abobotulinumtoxinA was conducted. In addition to the licensed indications, other special populations were considered for discussion. The...

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Bibliographic Details
Published in:Aesthetic surgery journal 2017-05, Vol.37 (suppl_1), p.S32-S44
Main Authors: Cohen, Joel L, Scuderi, Nicolo
Format: Article
Language:English
Subjects:
Antibodies, Neutralizing - immunology
Botulinum Toxins, Type A - administration & dosage
Botulinum Toxins, Type A - adverse effects
Botulinum Toxins, Type A - pharmacology
Cicatrix, Hypertrophic - therapy
Clinical Trials as Topic
Cosmetic Techniques - adverse effects
Facial Muscles - drug effects
Female
Humans
Injections, Intradermal
Injections, Intramuscular
Keloid - drug therapy
Neuromuscular Agents - administration & dosage
Neuromuscular Agents - adverse effects
Neuromuscular Agents - pharmacology
Patient Satisfaction
Pregnancy - drug effects
Skin Aging - drug effects
Supplement
Surveys and Questionnaires
Treatment Outcome
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Summary:A systematic review of the published literature (from January 2000 to January 2016) to ascertain the safety of, and patient satisfaction with, the aesthetic use of abobotulinumtoxinA was conducted. In addition to the licensed indications, other special populations were considered for discussion. The potential impact of neutralizing antibodies and systemic toxicity were also addressed. A total of 364 papers were screened and 86 were found to be relevant to the population, intervention(s), and outcomes stipulated in the protocol. The safety and patient satisfaction data from these publications are discussed in this review.
ISSN:1090-820X
1527-330X
DOI:10.1093/asj/sjx010