Delay of insulin initiation in patients with type 2 diabetes mellitus inadequately controlled with oral hypoglycemic agents (analysis of patient‐ and physician‐related factors): A prospective observational DIPP‐FACTOR study in Korea

Aims/Introduction To assess the time to initiation of insulin therapy, and concurrently investigate both patient‐ and physician‐related factors associated with delaying insulin therapy in Korean patients with type 2 diabetes uncontrolled by oral hypoglycemic agents (OHAs). Materials and Methods This...

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Published in:Journal of diabetes investigation 2017-05, Vol.8 (3), p.346-353
Main Authors: Kim, Sin Gon, Kim, Nam Hoon, Ku, Bon Jeong, Shon, Ho Sang, Kim, Doo Man, Park, Tae Sun, Kim, Yong‐Seong, Kim, In Joo, Choi, Dong Seop
Format: Article
Language:English
Subjects:
Administration, Oral
Adult
Diabetes
Diabetes mellitus
Diabetes Mellitus, Type 2 - drug therapy
Female
Glucose
Hemoglobin
Humans
Hypoglycemia
Hypoglycemic agents
Hypoglycemic Agents - administration & dosage
Hypoglycemic Agents - therapeutic use
Insulin
Insulin - administration & dosage
Insulin - therapeutic use
Insulin therapy
Male
Middle Aged
Original
Patient Participation
Patients
Physician and patient behaviors
Physician-Patient Relations
Prospective Studies
Registries
Republic of Korea
Type 2 diabetes
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Summary:Aims/Introduction To assess the time to initiation of insulin therapy, and concurrently investigate both patient‐ and physician‐related factors associated with delaying insulin therapy in Korean patients with type 2 diabetes uncontrolled by oral hypoglycemic agents (OHAs). Materials and Methods This prospective, observational disease registry study was carried out across 69 centers in Korea. Type 2 diabetes patients who had received two or more OHAs within the past 5 years, had a glycated hemoglobin ≥8% in the past 6 months and had not received insulin were included. Data recorded on data collection forms during a 12‐month period were analyzed. Results Of 2168 patients enrolled, 1959 were evaluated and classified as the insulin‐initiated or insulin‐delayed group. Insulin was prescribed for just 20% of the patients during a 1‐year follow‐up period, and less than half (44.5%) of the patients who were taking two OHAs started insulin after 6 years. Patient‐related factors for delay in insulin initiation included older age, shorter duration of diabetes and lower glycated hemoglobin. Physician‐related factors included age (~50 to
ISSN:2040-1116
2040-1124
DOI:10.1111/jdi.12581