Evaluation of human epidermal growth factor receptor 2 in breast cancer with a novel specific aptamer

Human epidermal growth factor receptor 2 （HER2）, also known as Neu, ErbB-2, CD340 or p185, plays a significant role in the devdopment and progression of certain aggressive types of breast cancer. Recently, HER2 has become an important biomarker and therapeutic target for approximately 30% of breast...

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Bibliographic Details
Published in:Cellular & molecular immunology 2017-04, Vol.14 (4), p.398-400
Main Authors: Chu, Ming, Kang, Jia-Rui, Wang, Wei, Li, Haichao, Feng, Jia-Hui, Chu, Zheng-Yun, Zhang, Ming-Bo, Xu, Lan, Wang, Yue-Dan
Format: Article
Language:English
Subjects:
Aptamers
Aptamers, Nucleotide - metabolism
Breast cancer
Breast Neoplasms - metabolism
Breast Neoplasms - pathology
Cell Line, Tumor
Epidermal growth factor
Female
Humans
Letter to the Editor
Receptor, ErbB-2 - metabolism
SELEX Aptamer Technique
乳腺癌
应用
攻击类型
生物标志物
神经
表皮生长因子受体
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Summary:Human epidermal growth factor receptor 2 （HER2）, also known as Neu, ErbB-2, CD340 or p185, plays a significant role in the devdopment and progression of certain aggressive types of breast cancer. Recently, HER2 has become an important biomarker and therapeutic target for approximately 30% of breast cancer patients.
ISSN:1672-7681
2042-0226
DOI:10.1038/cmi.2015.31