Compressed single pixel imaging in the spatial frequency domain

We have developed compressed sensing single pixel spatial frequency domain imaging (cs-SFDI) to characterize tissue optical properties over a wide field of view (35  mm×35  mm) using multiple near-infrared (NIR) wavelengths simultaneously. Our approach takes advantage of the relatively sparse spatia...

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Bibliographic Details
Published in:Journal of biomedical optics 2017-03, Vol.22 (3), p.030501-030501
Main Authors: Torabzadeh, Mohammad, Park, Il-Yong, Bartels, Randy A, Durkin, Anthony J, Tromberg, Bruce J
Format: Article
Language:English
Subjects:
JBO Letters
Letter
Optical Imaging - instrumentation
Optical Imaging - methods
Phantoms, Imaging
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Summary:We have developed compressed sensing single pixel spatial frequency domain imaging (cs-SFDI) to characterize tissue optical properties over a wide field of view (35  mm×35  mm) using multiple near-infrared (NIR) wavelengths simultaneously. Our approach takes advantage of the relatively sparse spatial content required for mapping tissue optical properties at length scales comparable to the transport scattering length in tissue (ltr∼1  mm) and the high bandwidth available for spectral encoding using a single-element detector. cs-SFDI recovered absorption (μa) and reduced scattering (μs′) coefficients of a tissue phantom at three NIR wavelengths (660, 850, and 940 nm) within 7.6% and 4.3% of absolute values determined using camera-based SFDI, respectively. These results suggest that cs-SFDI can be developed as a multi- and hyperspectral imaging modality for quantitative, dynamic imaging of tissue optical and physiological properties.
ISSN:1083-3668
1560-2281
DOI:10.1117/1.JBO.22.3.030501