Effects of Weight Loss on Lean Mass, Strength, Bone, and Aerobic Capacity

PURPOSETo evaluate the hypothesis that exercise attenuates the reductions in lean mass, muscle strength, BMD, and VO2max that accompany modest weight loss induced by calorie restriction. METHODSOverweight, sedentary women and men (n=52, 45–65y) were randomized to 6-8% weight loss by using calorie re...

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Bibliographic Details
Published in:	Medicine and science in sports and exercise 2017-01, Vol.49 (1), p.206-217
Main Authors:	Weiss, Edward P, Jordan, Richard C, Frese, Ethel M, Albert, Stewart G, Villareal, Dennis T
Format:	Article
Language:	eng
Subjects:	Aged Body Mass Index Bone Density Caloric Restriction Energy Metabolism - physiology Exercise Therapy Humans Middle Aged Muscle Strength - physiology Overweight - therapy Oxygen Consumption - physiology Physical Conditioning, Human Weight Loss - physiology
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Summary:	PURPOSETo evaluate the hypothesis that exercise attenuates the reductions in lean mass, muscle strength, BMD, and VO2max that accompany modest weight loss induced by calorie restriction. METHODSOverweight, sedentary women and men (n=52, 45–65y) were randomized to 6-8% weight loss by using calorie restriction (CR), endurance exercise (EX), or both (CREX). The CR and CREX groups underwent counseling to reduce energy intake by 20% and 10%, respectively. The EX and CREX groups exercised 7.4±0.5 and 4.4±0.5 hr/wk, respectively. Before and after 16.8±1.1 weeks of weight loss, lean mass and BMD were measured with dual-energy X-ray absorptiometry, strength was measured with dynamometry, and aerobic capacity (VO2max) was measured with indirect calorimetry during maximal-intensity treadmill exercise. RESULTSWeight loss was ~7% in all groups. Decreases in whole body (~2%, p=0.003) and lower extremity (~4%, p
ISSN:	0195-9131 1530-0315