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Syk kinase and Shp2 phosphatase inhibition cooperate to reduce FLT3-ITD-induced STAT5 activation and proliferation of acute myeloid leukemia

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Bibliographic Details
Published in:	Leukemia 2016-10, Vol.30 (10), p.2094-2097
Main Authors:	Richine, B M, Virts, E L, Bowling, J D, Ramdas, B, Mali, R, Naoye, R, Liu, Z, Zhang, Z-Y, Boswell, H S, Kapur, R, Chan, R J
Format:	Article
Language:	English
Subjects:	Acute myelocytic leukemia Acute myeloid leukemia Amino Acid Sequence Care and treatment Cell Proliferation Enzyme Inhibitors - pharmacology fms-Like Tyrosine Kinase 3 - chemistry fms-Like Tyrosine Kinase 3 - physiology Health aspects Humans Hypotheses Kinases Letters to the editor Leukemia Leukemia, Myeloid, Acute - metabolism Leukemia, Myeloid, Acute - pathology Medical prognosis Mutation Phosphatase Phosphatases Phosphorylation Phosphotransferases Protein Tyrosine Phosphatase, Non-Receptor Type 11 - antagonists & inhibitors Proteins Sequence Homology, Amino Acid Stat5 protein STAT5 Transcription Factor - metabolism Syk Kinase - antagonists & inhibitors Syk protein
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