Breast carcinoma cellularity and its relation to oestrogen receptor content

The cellularity of 104 primary breast carcinomata was determined by semiautomated image analysis to allow the relation between cellularity and oestrogen receptor content values to be assessed. The oestrogen receptor content of tumours detected by a steroid binding assay showed no correlation with ce...

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Bibliographic Details
Published in:Journal of clinical pathology 1989-11, Vol.42 (11), p.1166-1168
Main Authors: Parham, D M, Baker, P R, Robertson, A J, Vasishta, A, Baker, P G, Smith, G
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Breast Neoplasms - analysis
Breast Neoplasms - pathology
Female
Gynecology. Andrology. Obstetrics
Humans
Mammary gland diseases
Medical sciences
Middle Aged
Receptors, Estrogen - analysis
Retrospective Studies
Tumors
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Summary:The cellularity of 104 primary breast carcinomata was determined by semiautomated image analysis to allow the relation between cellularity and oestrogen receptor content values to be assessed. The oestrogen receptor content of tumours detected by a steroid binding assay showed no correlation with cellularity, although a possible weak negative correlation was observed between tumour cellularity and oestrogen receptor content detected by enzyme immunoassay. It is concluded that there is no single direct correlation between tumour cellularity and oestrogen receptor content.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.42.11.1166