Tissue distribution of organochlorine pesticides in largemouth bass (Micropterus salmoides) from laboratory exposure and a contaminated lake

Tissue concentrations of persistent organochlorine pesticides in laboratory-exposed largemouth bass (Micropterus salmoides) and in bass collected from Lake Apopka, FL were determined by both total mass and lipid normalized mass to better understand the bioaccumulation pathways of contaminants. In th...

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Bibliographic Details
Published in:Environmental pollution (1987) 2016-09, Vol.216, p.877-883
Main Authors: Dang, Viet D., Kroll, Kevin J., Supowit, Samuel D., Halden, Rolf U., Denslow, Nancy D.
Format: Article
Language:English
Subjects:
Animals
Bass - growth & development
Bass - metabolism
DDT - analysis
DDT - pharmacokinetics
Dichlorodiphenyl Dichloroethylene - analysis
Dichlorodiphenyl Dichloroethylene - pharmacokinetics
Dieldrin - metabolism
Dieldrin - pharmacokinetics
Hydrocarbons, Chlorinated - analysis
Hydrocarbons, Chlorinated - pharmacokinetics
Lake Apopka
Lakes - chemistry
Largemouth bass
Lindane - analysis
Lindane - pharmacokinetics
Male
Models, Theoretical
Oral dosing
Organ Specificity
Organochlorine pesticides
Pesticides - analysis
Pesticides - pharmacokinetics
Tissue concentration
Tissue Distribution
Water Pollutants, Chemical - analysis
Water Pollutants, Chemical - pharmacokinetics
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Summary:Tissue concentrations of persistent organochlorine pesticides in laboratory-exposed largemouth bass (Micropterus salmoides) and in bass collected from Lake Apopka, FL were determined by both total mass and lipid normalized mass to better understand the bioaccumulation pathways of contaminants. In the laboratory study, male bass were orally administered a single dose of a mixture of two pesticides (p,p′-dichlorodiphenyldichloroethylene (p,p′-DDE) and dieldrin) and then fed uncontaminated food for 28 days. Gastrointestinal tract, liver, brain, gonad, kidney, spleen, and muscle were collected for chemical analysis. Different profiles were observed by total contaminant mass in tissues compared to lipid normalized mass. On a lipid normalized basis, p,p′-DDE was highest in the gastrointestinal tract followed by the liver, gonad, spleen, muscle, kidney and then brain. Dieldrin, on the other hand, was highest in the gastrointestinal tract and spleen and then followed by the gonad, muscle, liver, kidney, and brain. Distribution of the chemicals among the organs differed by their log KOW values and generally followed the blood flow path after the gastrointestinal tract. The low contaminant levels found in kidney and brain suggest insufficient time for equilibration into these tissues, especially into the brain where the blood-brain barrier may be slow to traverse. In Lake Apopka fish, dichlorodiphenyltrichloroethanes (DDXs, sum of p,p′-DDE, p,p′-DDD, and p,p′-DDT), Drins (sum of aldrin, dieldrin, and endrin), and hexachlorocyclohexanes (HCHs) were found. For DDXs, the lipid normalized concentrations in each tissue were about the same, as predicted from theory. For Drins and HCHs, the lipid normalized concentrations were similar for kidney, spleen, brain, gonad and muscle, but much lower in the gastrointestinal tract and liver, probably because of metabolism occurring in those tissues. [Display omitted] •Tissue distribution of organochlorine pesticides in laboratory exposed and wild-caught largemouth bass was investigated.•Chemical concentrations were the highest in gastrointestinal tract for orally dosed bass.•Bioaccumulation of pesticides in tissues was associated with their KOW values.•Lipid normalized concentrations of pesticides were similar in each tissue of wild-caught fish.
ISSN:0269-7491
1873-6424
DOI:10.1016/j.envpol.2016.06.061