Amie Skilton, nd, bhsc: Inflammation in the Gut Drives Systemic Inflammation

Amie Skilton, nd, bhsc: Inflammation in the Gut Drives Systemic Inflammation

[...]the production of sIgA is a key component of maintaining immunological tolerance; it exerts its anti-inflammatory effects in a number of ways, including by reducing bacteria-induced proinflammatory circuits, and it can mediate a potent anti-inflammatory function following the sugar-dependent in...

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Bibliographic Details
Published in:Integrative medicine (Encinitas, Calif.) Calif.), 2016-08, Vol.15 (4), p.32-34
Main Author: Gustafson, Craig
Format: Article
Language:eng
Subjects:
Alcohol
Chronic illnesses
Cytokines
Digestive system
Fatty acids
Immune system
Immunology
Infections
Inflammation
Integrative medicine
Medicine
Microorganisms
Presenters 2016
Womens health
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Summary:[...]the production of sIgA is a key component of maintaining immunological tolerance; it exerts its anti-inflammatory effects in a number of ways, including by reducing bacteria-induced proinflammatory circuits, and it can mediate a potent anti-inflammatory function following the sugar-dependent interaction with SIGNR1 on dendritic cells, which induces an immune tolerance via regulatory T-cell expansion. [...]ensuring appropriate gastrointestinal permeability also reduces immunological provocation by reducing the passage of lipopolysaccharide, or LPS, and macromolecular translocation. [...]they are responsible for short-chain fatty acid, or SCFA, synthesis.
ISSN:1546-993X
1945-7081